Nano Vs Micro Hydroxyapatite: What's the Difference?

Nano-Hydroxyapatite versus Micro-Hydroxyapatite: Which one is better?

Hydroxyapatite, a naturally occurring calcium phosphate mineral, is the primary building block of our teeth and bones. It comprises 97% of tooth enamel and plays a crucial role in maintaining oral health by reinforcing enamel, preventing demineralization, and reducing tooth sensitivity. Recognizing its benefits, a biomimetic version of hydroxyapatite was created in the 1970s as an ingredient in toothpaste to remineralize enamel, replicating the natural process that occurs in our teeth.

Understanding Hydroxyapatite: A Key Player in Oral Health

Hydroxyapatite naturally strengthens and remineralizes enamel, acting as a barrier against cavities, sensitivity, and enamel erosion. It bonds directly to the tooth surface, filling micro-cracks and restoring enamel’s smoothness and strength. This process also enhances the natural appearance of teeth by filling in imperfections that dull the surface.

Nano vs. Micro Hydroxyapatite: Size Matters

The size of hydroxyapatite particles determines how deeply they can penetrate tooth enamel and the extent of their benefits:

Nano-Hydroxyapatite (Nano-HA):

• Particles are 20-100 nanometers in size.

• Penetrates deeper into enamel to repair micro-cracks and rebuild structure.

• Mimics natural enamel for seamless bonding.

• Reduces sensitivity by sealing microscopic pathways to nerves.

• Buffers enamel against acidic attacks, making it an ideal choice for brushing before meals, especially breakfast, as brushing immediately after eating or drinking is not recommended for 30-60 minutes.

Micro-Hydroxyapatite (Micro-HA):

• Particles are 5-10 microns in size.

• Focuses on surface-level enamel protection.

• Reinforces the enamel’s outer layer against wear and tear.

• More affordable but less effective at deep remineralization compared to nano-HA.

 

The 5 Key Benefits of Nano-Hydroxyapatite

1. Deep Remineralization: Repairs enamel at a microscopic level, reversing early signs of demineralization.

2. Natural Whitening: Fills surface cracks for a smoother, brighter appearance without harsh bleaching agents.

3. Sensitivity Reduction: Seals pathways to nerves, significantly reducing discomfort.

4. Acid Resistance: Buffers enamel against acidic attacks, helping protect teeth from diet-related erosion.

5. Microbe Interaction: Nano-HA’s ultra-small size enables it to bind to oral microbes effectively, significantly reducing plaque while maintaining the balance of the oral microbiome. This provides a safe and gentle alternative to alcohol-based or antiseptic products.

Safety Considerations: Both Nano and Micro Are Proven Safe

• Micro-hydroxyapatite has been used safely in dental care since the 1970s, while nano-hydroxyapatite has been in use since the 1980s.

• Approved in many countries, including Japan, Canada, and Europe, both forms have undergone extensive testing for decades and are considered incredibly safe for children, adults, and pregnant women.

• Current research confirms that nano-HA does not cross the blood-brain barrier or accumulate in the body when used in oral care products.

Which Should You Choose?

• Nano-Hydroxyapatite: Ideal for those with sensitivity, early enamel erosion, or anyone seeking advanced enamel repair and whitening benefits.

• Micro-Hydroxyapatite: A more affordable option for maintaining surface-level enamel strength.

The SuperMouth Difference

At SuperMouth, we harness the power of nano-hydroxyapatite in all our oral care products, including toothpastes, mouthwashes, and flosses, ensuring optimal concentrations for maximum efficacy.

Our proprietary Hydroxamin formulation combines nano-HA with vitamins D3 and K2, addressing a common deficiency in the population. These vitamins are essential for enhancing calcium absorption into teeth, further strengthening enamel and supporting overall oral health. Additionally, by incorporating natural prebiotics, we nurture the delicate balance of the oral microbiome, promoting long-term oral wellness. SuperMouth provides safe, effective, and family-friendly solutions designed to meet the needs of every age and stage.

FAQ: Nano vs. Micro Hydroxyapatite

Can I use both nano and micro hydroxyapatite products?

While both forms offer benefits, some studies caution against mixing them in a single product. Micro particles may bond to nano particles, potentially reducing nano-HA’s deep remineralization effectiveness. It’s best to use products formulated with one type at a time.

Are nano and micro hydroxyapatite safe?

Yes, both have been extensively studied and are safe for children, adults, and pregnant women. They do not cross the blood-brain barrier or accumulate in the body.

How long does it take to see results with nano-hydroxyapatite?

Improvements in enamel strength and sensitivity reduction can be noticeable within a few weeks of consistent use.

Does nano-hydroxyapatite whiten teeth?

Yes, nano-HA naturally whitens teeth by filling surface cracks and smoothing enamel, enhancing their reflectivity.

Why choose SuperMouth’s Hydroxamin?

SuperMouth combines nano-HA with vitamins D3 and K2 for enhanced enamel support, safety, and effectiveness. Our products also nourish the oral microbiome and are free from harsh chemicals, making them ideal for the entire family.

 

Disclaimer: This article is for informational purposes only and is not intended to replace professional dental advice. Consult a healthcare professional for personalized oral care guidance.

 

Supporting Studies:

1. Wierichs, R.J., Wolf, T.G., Campus, G. et al. Efficacy of nano-hydroxyapatite on caries prevention—a systematic review and meta-analysis. Clin Oral Invest 26, 3373–3381 (2022). https://doi.org/10.1007/s00784-022-04390-4
2. Klaessig, F.C. Nano-hydroxyapatite Before the Science Court. Nanoethics 17, 7 (2023). https://doi.org/10.1007/s11569-023-00442-5
3. Clinical efficacy of nanohydroxyapatite-containing toothpaste at relieving dentin hypersensitivity https://www.nature.com/articles/s41405-021-00080-7.pdf
4. Pepla E, Besharat LK, Palaia G, Tenore G, Migliau G. Nano-hydroxyapatite and its applications in preventive, restorative and regenerative dentistry: a review of literature. Ann Stomatol (Roma). 2014 Nov 20;5(3):108-14. PMID: 25506416; PMCID: PMC4252862.
5. Tschoppe P, Zandim DL, Martus P, Kielbassa AM. Enamel and dentine remineralization by nano-hydroxyapatite toothpastes. J Dent. 2011 Jun;39(6):430-7. doi: 10.1016/j.jdent.2011.03.008. Epub 2011 Apr 8. PMID: 21504777.
6. European Scientific Committee on Consumer Safety – Opinion on Hydroxyapatite (nano) 2021 & 2023.https://health.ec.europa.eu/publications/hydroxyapatite-nano-0_en
7. Izzetti R, Gennai S, Nisi M, Gulia F, Miceli M, Giuca MR. Clinical Applications of Nano-Hydroxyapatite in Dentistry. Applied Sciences. 2022; 12(21):10762. https://doi.org/10.3390/app122110762